021-51111890
购物车（）
sales@molnova.cn
BI 1467335
CAS No. 1478364-68-9
BI 1467335 ( PXS-4728A;PXS-4728 )
产品货号. M12040 CAS No. 1478364-68-9
BI 1467335 (PXS-4728A,PXS-4728) is a potent, selective, orally active SSAO/VAP-1 (AOC3) inhibitor with IC50 of 5 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥502 | 有现货 |
|
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1320 | 有现货 |
|
| 25MG | ￥2811 | 有现货 |
|
| 50MG | ￥4496 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称BI 1467335
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述BI 1467335 (PXS-4728A,PXS-4728) is a potent, selective, orally active SSAO/VAP-1 (AOC3) inhibitor with IC50 of 5 nM.
-
产品描述BI 1467335 (PXS-4728A,PXS-4728) is a potent, selective, orally active SSAO/VAP-1 (AOC3) inhibitor with IC50 of 5 nM; displays >500-fold selective for VAP-1/SSAO over all the related human amine oxidases; diminishes leukocyte rolling and adherence induced by CXCL1/KC, also inhibits the migration of neutrophils to the lungs in response to LPS, Klebsiella pneumoniae lung infection and CLP induced sepsis.Steatohepatitis,Phase 2 Clinical
-
同义词PXS-4728A;PXS-4728
-
通路Others
-
靶点Other Targets
-
受体Other Targets
-
研究领域Other Indications
-
适应症Steatohepatitis
化学信息
-
CAS Number1478364-68-9
-
分子量316.80
-
分子式C15H21FN2O2.HCl
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCC(C)(C)NC(=O)C1=CC=C(C=C1)OCC(=CF)CN.Cl
-
化学全称(E)-4-((2-(aminomethyl)-3-fluoroallyl)oxy)-N-(tert-butyl)benzamide hydrochloride
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Schilter HC, et al. Respir Res. 2015 Mar 20;16:42.
2. Jarnicki AG, et al. Br J Pharmacol. 2016 Nov;173(22):3161-3175.
3. Katagiri D, et al. Respir Res. 2015 Mar 20;16:42.
2. Jarnicki AG, et al. Br J Pharmacol. 2016 Nov;173(22):3161-3175.
3. Katagiri D, et al. Respir Res. 2015 Mar 20;16:42.
产品手册
关联产品
-
Toddaculin
Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways.
-
6-Hydroxy-4-methylco...
6-Hydroxy-4-Methylcoumarin is a useful research chemical.
-
PEN (mouse)
Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide. Activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus.
